how can i compute euclidean distance between 2 consecutive points of a manifold curve

hello im working on echocardiography datas. i have a manifold curve for about 80 images, so each image is a point in manifold curve. i need to compute distance between consecutive frames( points) to find the 2 most nearest and farest frames(points). i need to compute the euclidean distance between each 2 points but i dont know how. this is my matlab code for manifold curve:

clear all; close all; clc;

Image_Address_Echo_1='E:\shadi gholipoor\manifold\4-chamber view\frames\';

file_format_Echo='.jpg';

for num=1:84

      prefix_image='4-chamber view';

      Image= rgb2gray(imread(strcat(Image_Address_Echo_1,prefix_image,num2str(num),file_format_Echo)));

      Row_Col_Input_Image= size(Image);

      Input_Dataset1(num,:)= reshape(Image,1,(Row_Col_Input_Image(1,1)*Row_Col_Input_Image(1,2)));

end

Output_Echo_LLE_8_Dataset1 = compute_mapping(Input_Dataset1, 'LLE',2,8);

plot(Output_Echo_LLE_8_Dataset1(:,1),Output_Echo_LLE_8_Dataset1(:,2),'.r-'),title('LLE, 8,gholipoor 4chamber view')