How to create response surface and multi objective optimization using external simulated DOE data.

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Hi all,
Using a FEA simulation software I have obtained simlation results for two objective functions when three variables varied in a certain design space. The data is stored in a excel file and I need to generate reponse surface in MATLAB and use the response surface to perform Multi objective optmization inside MATLAB.
How can this be done?
Any suggestions would be higly appreciated.
Best Regards,
Rashiga

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