Bispecific Protein Degrader PK-PD Model for SimBiology

Versione 1.0.2 (161 KB) da Derek Bartlett
SimBiology project file for a published PK-PD model for bispecific protein degraders
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Aggiornato 31 mag 2023

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The SimBiology model described in the following publication:
Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z
Please note that some of the included visualizations require the "gridfit" routine written by John D'Errico: Surface Fitting using gridfit (https://www.mathworks.com/matlabcentral/fileexchange/8998-surface-fitting-using-gridfit), MATLAB Central File Exchange.

Cita come

Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z

Compatibilità della release di MATLAB
Creato con R2022a
Compatibile con R2022a e release successive
Compatibilità della piattaforma
Windows macOS Linux
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Versione Pubblicato Note della release
1.0.2

Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology.
1.0.1

Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology.
1.0.0