How to do uneven 2 way anova

I have some unbalanced data (below are the subject names) . How can I run a 2 way anova on this?

Group 1 Group 2

'1013_2_45 1013_2_45'

'1017_2_23 1016_2_34'

'1038_2_23 1017_2_23'

'1039_2_24 1028_2_23'

'1042_2_26 1029_2_34'

'1049_2_23 1032_2_56'

'1060_2_67 1049_2_23'

'1063_2_45 1060_2_67'

'1066_2_23 1063_2_45'

'1084_2_24 1066_2_23'

Answer 1

[the cyclist]

The documentation for anovan has an example for two-way ANOVA for unbalanced design.