How to interpolate empty gridcells in the 3D model?

I have a 3D model of size ss = 139 48 101 which has a lot inactive cell having values NaN and therefore appears empty space shown in the figure below. I do not want empty and want to interpolate the iactive cells by using nearby values. How I can do it - interpolation based on near by data values (instead of taking NaN as a single contant).
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