generalize code for different images

I am working on a project to make automatic diagnosis through MRI images.I have some challenges: 1- Image size is not the same because of different resources some exported to be 504*504 and some is 1344*615 (I use paint program to crop the image but I doubt it can affect the image) 2-Each image needs different threshold value for segmentation. 3- Not all the series of images for all patients have the same intensity levels.

can you help me please to overcome these challenges.

Answer 1

[Image Analyst]

I bet radiologists love you ( NOT!). Anyway, assuming you did find a radiologist willing and confident enough to turn over his job to a computer program, your #1 is not a problem. Not sure why you think it is. Who cares if the image are different sizes? It's normally not a problem.

For #2, you can try my interactive/visual thresholding application: http://www.mathworks.com/matlabcentral/fileexchange/29372-thresholding-an-image or else write your own routine. Most likely a simple intensity thresholding will not be robust to the wide variety of pathologies you can expect to encounter. But, what they heck, give it a try as a learning experience.

For #3, this will be dealt with as part of your thresholding algorithm in #2. It's not really a separate issue.