How do I speed up 4 nested loops?

I need to test different variables for thresholds and parameters to get the optimal ones for an algorithm... so the pseudo code is

 for threshold1=1:10
   for threshold2=1:10
     for parameter1=1:10
       for parameter2=1:10
         Apply algorithm using the 4 values and evaluate
         Compare to previous best results, if better then override
       end
    end
  end
end

[Stephen23]

Write vectorized code instead of using loops.

Answer 1

[Jan]

There is no magic trick to accelerate the loops. The point which can be improved is hidden in the text "Apply algorithm". Can this algorithm be vectorized, such it replies a vector of values for the input parameter2 = 1:10.

Using a local optimization method would be smart, if the reply of teh "algorithm" is smooth and has one local minimum only.