Hello, I passed enormous time trying to fit the model in Simbiology unsuccessfully . Using the initial values is not enough for model fitting, and I need to define limits for the variables. How is it possible?
If you are using the functionsbiofit from the command line, you can specify bounds using theestimatedInfo input argument as describedhere. You can also specify bounds in the Fit Task in the SimBiology desktop. You can find a more extensive examplehere.
You may also want to try using a global optimization likescattersearch.