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How does SimBiology calculate the "lambda" in NCA?

Asked by Seokuee Kim on 16 Oct 2018
Latest activity Commented on by Seokuee Kim on 16 Oct 2018
I was wonder that How does SimBiology calculate the "lambda" in NCA?
When I use WinNonlin, I can choice the weighting option in linear regression (ex. unweighted, 1/y, 1/y^2).
Although SimBiology doesn't provide the weighting option, I think that Simbiology uses any one of above.
Thank you.

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1 Answer

Answer by Arthur Goldsipe on 16 Oct 2018
 Accepted Answer

Hi,
Currently (as of R2018b), SimBiology's NCA uses linear regression with all of the points weighted equally. I'm guessing that's what you would call "unweighted."
-Arthur

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Thank you for your prompt answer!!

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