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How to perform image processing on raw DICOM medical data?

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I have received a raw DICOM medical pet data with over 5000 files. I would like to perform image processing on them in MATLAB. I have tried to adjust the threshold level in AMIDE but I have no idea whether to convert them to .dcm or .xif. Each file has 25 time frames.
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Image Analyst
Image Analyst il 3 Gen 2016
What is AMIDE? How are thresholds determined in it?
When you say "them", to what do you refer? To the threshold levels (which is the subject of that sentence)?

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Walter Roberson
Walter Roberson il 3 Gen 2016
Use dcm files. In MATLAB, use dicomread(). The output of that will be a 4D array, width by height by 1 by timestep

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