SimBiology

Segui

I am dealing with a PBPK model in Simbiology. I have two parameters that, when both are modified even of orders of magnitute, the simulation remains exactly the same. I figured I have some issues with identifiability. I found that GenSSI is a useful tool that can provide some insights on the structural identifiability of the model's parameters. However, I cannot understand how to import the Simbiology-based model in such a way that I can use this program. Can somebody provide suggestions/tutorial?

When trying to import an SBML file to use in SimBiology, I am getting the following error >> x = sbmlimport('http://www.netpath.org/netslim/EGFR1/EGFR1_SBML.xml') Error using SimBiology.SBMLReadWrite/sbmlread A fatal error occurred reading in this file. Error in sbmlimport (line 96) ret = sbmlRW.sbmlread(modelString, {'stream'}); A similar error occurs if the linked file above is downloaded and added to the path instead. ( Throwing an error on line 89: ret = privatesbmlio('read',nargout,{tempFileName}); ) Why is this happening? How can I fix it?

Functions to import SBML files containing function definitions into SimBiology.

I have a simbiology file from a published article, so theoretically it should work. I am trying to extract the equations using bb=sbmlimport('filename') equations=getequations(bb) I get a lot of warnings when i import the file ("duplicate reaction names not allowed"), and when i try to get the equations it says "error reported from dimensional analysis". (same error as when attempting to simulate). I tried to verify it, and it gives the same error messages and throws a 1x2191 array of errors. (so every single reaction). I tried to import using the app, but it crashes when it throws the first warning. This is my first time using simbiology, so perhaps theres some setting or something I'm missing? I'm using matlab R2015b, and I have the toolbox.